Model-driven mitigation measures for reopening schools during the COVID-19 pandemic

1

Posted: 2021-09-14 19:00:00
Proc Natl Acad Sci U S A . 2021 Sep 28;118(39):e2108909118. doi: 10.1073/pnas.2108909118. Affiliations Expand Affiliations 1 Department of Biology, University of Washington, Seattle, WA 98195; ryansmcgee@gmail.com. 2 Scientific Affairs, Color Health, Burlingame, CA 94010. 3 Department of Biology, University of Washington, Seattle, WA 98195. Item in Clipboard Ryan Seamus McGee et al. Proc Natl Acad Sci U S A. 2021. Show details Display options Display options Format Proc Natl Acad Sci U S A . 2021 Sep 28;118(39):e2108909118. doi: 10.1073/pnas.2108909118. Affiliations 1 Department of Biology, University of Washington, Seattle, WA 98195; ryansmcgee@gmail.com. 2 Scientific Affairs, Color Health, Burlingame, CA 94010. 3 Department of Biology, University of Washington, Seattle, WA 98195. Item in Clipboard CiteDisplay options Display options Format Abstract Reopening schools is an urgent priority as the COVID-19 pandemic drags on. To explore the risks associated with returning to in-person learning and the value of mitigation measures, we developed stochastic, network-based models of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in primary and secondary schools. We find that a number of mitigation measures, alone or in concert, may reduce risk to acceptable levels. Student cohorting, in which students are divided into two separate populations that attend in-person classes on alternating schedules, can reduce both the likelihood and the size of outbreaks. Proactive testing of teachers and staff can help catch introductions early, before they spread widely through the school. In secondary schools, where the students are more susceptible to infection and have different patterns of social interaction, control is more difficult. Especially in these settings, planners should also consider testing students once or twice weekly. Vaccinating teachers and staff protects these individuals and may have a protective effect on students as well. Other mitigations, including mask wearing, social distancing, and increased ventilation, remain a crucial component of any reopening plan. Keywords: SARS-CoV-2; epidemiology; primary schools; secondary schools. Copyright © 2021 the Author(s). Published by PNAS. Conflict of interest statement Competing interest statement: C.T.B. and R.S.M. consult for Color Health. C.T.B. has received honoraria from Novartis. H.E.W. and A.Y.Z. are currently employed by and have equity interest in Color Health. J.R.H. was previously employed by and holds an equity stake in Color Health. J.R.H. is currently employed and has an equity interest in Maze Therapeutics. References United Nations Educational, Scientific and Cultural Organization. Hanushek E., Woessmann L.. The economic impacts of learning losses. Nierenberg A., Pasick A.. Will any more schools reopen in 2020?. NY Times. Leidman E.. COVID-19 trends among persons aged 0–24 years — United States, March 1–December 12, 2020. MMWR Morb. Mortal. Wkly. Rep.. 2021;70:88–94. Walensky R. P., Walke H. T., Fauci A. S.. SARS-CoV-2 variants of concern in the United States challenges and opportunities. JAMA. 2021;325:1037–1038. Show all 77 references [x] Cite Copy Format: Send To [x]

参考サイト PubMed: covid-19



バイオクイックニュース日本語版:COVID-19特集

バイオクイックニュース日本語版
12月 04, 2020 bioassociates2

なぜ子供はCOVID-19にかかりにくいのか?その鍵となるファクターが特定された。

ヴァンダービルト大学医療センター(VUMC)の研究者らは、 COVID-19 が成人や高齢者に優先的に感染して発症する一方で、幼い子供には感染しにくいように見える理由について鍵となるファクターを特定した。 COVID-19を引き起こすRNAウイルスであるSARS-CoV-2が、肺の気道上皮細胞に侵入するのに必要な酵素/補助受容体であるTMPRSS2(画像)のレベルが大人より子供の方が低くかった。2020年11月12日にJournal of Clinical…

ゲスト 738人 と メンバー 7人 がオンラインです