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Lung Ultrasound Severity Index: Development and Usefulness in Patients with Suspected SARS-Cov-2 Pneumonia-A Prospective Study


Posted: 2021-09-22 19:00:00
Ultrasound Med Biol . 2021 Aug 31;S0301-5629(21)00373-2. doi: 10.1016/j.ultrasmedbio.2021.08.018. Online ahead of print. Affiliations Expand Affiliations 1 Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy. 2 University of Bologna Alma Mater Studiorum, Bologna, Italy. 3 Medical Semiotics Unit, University of Bologna Alma Mater Studiorum, Bologna, Italy. 4 Emergency Department, AUSL Bologna, Bologna, Italy. 5 Emergency Department, AUSL Bologna, Bologna, Italy. Electronic address: soccorsa.sofia@ausl.bologna.it. Item in Clipboard Michele Domenico Spampinato et al. Ultrasound Med Biol. 2021. Show details Display options Display options Format Ultrasound Med Biol . 2021 Aug 31;S0301-5629(21)00373-2. doi: 10.1016/j.ultrasmedbio.2021.08.018. Online ahead of print. Affiliations 1 Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy. 2 University of Bologna Alma Mater Studiorum, Bologna, Italy. 3 Medical Semiotics Unit, University of Bologna Alma Mater Studiorum, Bologna, Italy. 4 Emergency Department, AUSL Bologna, Bologna, Italy. 5 Emergency Department, AUSL Bologna, Bologna, Italy. Electronic address: soccorsa.sofia@ausl.bologna.it. Item in Clipboard CiteDisplay options Display options Format Abstract Coronavirus disease 2019 (COVID-19) has spread across the world with a strong impact on populations and health systems. Lung ultrasound is increasingly employed in clinical practice but a standard approach and data on the accuracy of lung ultrasound are still needed. Our study's objective was to evaluate lung ultrasound diagnostic and prognostic characteristics in patients with suspected COVID-19. We conducted a monocentric, prospective, observational study. Patients with respiratory distress and suspected COVID-19 consecutively admitted to the Emergency Medicine Unit were enrolled. Lung ultrasound examinations were performed blindly to clinical data. Outcomes were diagnosis of COVID-19 pneumonia and in-hospital mortality. One hundred fifty-nine patients were included in our study; 66% were males and 63.5% had a final diagnosis of COVID-19. COVID-19 patients had a higher mortality rate (18.8% vs. 6.9%, p = 0.04) and Lung Ultrasound Severity Index (16.14 [8.71] vs. 10.08 [8.92], p < 0.001) compared with non-COVID-19 patients. This model proved able to distinguish between positive and negative cases with an area under the receiver operating characteristic (AUROC) equal to 0.72 (95% confidence interval [CI]: 0.64-0.78) and to predict in-hospital mortality with an AUROC equal to 0.81 (95% CI: 0.74-0.86) in the whole population and an AUROC equal to 0.76 (95% CI: 0.66-0.84) in COVID-19 patients. The Lung Ultrasound Severity Index can be a useful tool in diagnosing COVID-19 in patients with a high pretest probability of having the disease and to identify, among them, those with a worse prognosis. Keywords: Emergency department; Lung ultrasound; Point-of-care-ultrasound; Prognostication; SARS-COV-2 pneumonia. Copyright © 2021 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved. Conflict of interest statement Conflict of interest disclosure The authors have no conflict of interest. [x] Cite Copy Format: Send To [x]

参考サイト PubMed: covid-19


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バイオクイックニュース日本語版:COVID-19特集

バイオクイックニュース日本語版
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