Learning through a Pandemic: The Current State of Knowledge on COVID-19 and Cancer

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Posted: 2021-12-11 20:00:00
Review Cancer Discov . 2021 Dec 10;candisc.1368.2021. doi: 10.1158/2159-8290.CD-21-1368. Online ahead of print. Arielle Elkrief 1 , Julie T Wu 2 , Chinmay Jani 3 , Kyle T Enriquez 4 , Michael Glover 5 , Mansi R Shah 6 , Hira Ghazal Shaikh 7 , Alicia Beeghly-Fadiel 8 , Benjamin French 9 , Sachin R Jhawar 10 , Douglas B Johnson 11 , Rana R McKay 12 , Donna R Rivera 13 , Daniel Y Reuben 14 , Surbhi Shah 15 , Stacey L Tinianov 16 , Donald Cuong Vinh 17 , Sanjay Mishra 18 , Jeremy L Warner 19 Affiliations Expand Affiliations 1 Hemato-Oncology, University of Montreal Research Center (CRCHUM). 2 Oncology, Stanford University. 3 Internal Medicine, Mount Auburn Hospital. 4 Medical Scientist Training Program, Vanderbilt University School of Medicine. 5 Internal Medicine, Stanford University. 6 Division of Blood Disorders, Rutgers Cancer Institute of New Jersey. 7 Hemaoology Oncology, University of Cincinnati Cancer Center. 8 Department of Medicine, Vanderbilt University Medical Center. 9 Vanderbilt University Medical Center. 10 Radiation Oncology, The Ohio State University Comprehensive Cancer Center. 11 Department of Medicine, Vanderbilt-Ingram Cancer Center. 12 Medicine, University of California, San Diego. 13 Oncology Center of Excellence, US FDA. 14 Hematology and Oncology, Medical University of South Carolina. 15 Mayo Clinic Hospital. 16 founder, Advocates for Collaborative Education. 17 McGill University Health Centre. 18 Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center. 19 Medicine and Biomedical Informatics, Vanderbilt University Medical Center jeremy.warner@vumc.org. Item in Clipboard Review Arielle Elkrief et al. Cancer Discov. 2021. Show details Display options Display options Format Cancer Discov . 2021 Dec 10;candisc.1368.2021. doi: 10.1158/2159-8290.CD-21-1368. Online ahead of print. Authors Arielle Elkrief 1 , Julie T Wu 2 , Chinmay Jani 3 , Kyle T Enriquez 4 , Michael Glover 5 , Mansi R Shah 6 , Hira Ghazal Shaikh 7 , Alicia Beeghly-Fadiel 8 , Benjamin French 9 , Sachin R Jhawar 10 , Douglas B Johnson 11 , Rana R McKay 12 , Donna R Rivera 13 , Daniel Y Reuben 14 , Surbhi Shah 15 , Stacey L Tinianov 16 , Donald Cuong Vinh 17 , Sanjay Mishra 18 , Jeremy L Warner 19 Affiliations 1 Hemato-Oncology, University of Montreal Research Center (CRCHUM). 2 Oncology, Stanford University. 3 Internal Medicine, Mount Auburn Hospital. 4 Medical Scientist Training Program, Vanderbilt University School of Medicine. 5 Internal Medicine, Stanford University. 6 Division of Blood Disorders, Rutgers Cancer Institute of New Jersey. 7 Hemaoology Oncology, University of Cincinnati Cancer Center. 8 Department of Medicine, Vanderbilt University Medical Center. 9 Vanderbilt University Medical Center. 10 Radiation Oncology, The Ohio State University Comprehensive Cancer Center. 11 Department of Medicine, Vanderbilt-Ingram Cancer Center. 12 Medicine, University of California, San Diego. 13 Oncology Center of Excellence, US FDA. 14 Hematology and Oncology, Medical University of South Carolina. 15 Mayo Clinic Hospital. 16 founder, Advocates for Collaborative Education. 17 McGill University Health Centre. 18 Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center. 19 Medicine and Biomedical Informatics, Vanderbilt University Medical Center jeremy.warner@vumc.org. Item in Clipboard CiteDisplay options Display options Format Abstract The ongoing COVID-19 pandemic has left patients with current or past history of cancer facing disparate consequences at every stage of the cancer trajectory. This comprehensive review offers a landscape analysis of the current state of the literature on COVID-19 and cancer including the immune response to COVID-19, risk factors for severe disease, and impact of anticancer therapies. We also review the latest data on treatment of COVID-19 and vaccination safety and efficacy in patients with cancer, as well as impact of the pandemic on cancer care, including the urgent need for rapid evidence generation and real-world study designs. Copyright ©2021, American Association for Cancer Research. Publication types [x] Cite Copy Format: Send To [x]

参考サイト PubMed: covid-19



バイオクイックニュース日本語版:COVID-19特集

バイオクイックニュース日本語版
9月 23, 2020 bioassociates2

既存薬物のエブセレンがCOVID-19の新しい治療戦略の開発に役立つ可能性

2019年後半に中国の武漢市で初めて出現したSARS-CoV-2ウイルスは、世界中で病気と死を引き起こしている。 既に承認された医薬品の転用を含め、 COVID-19 を治療するための複数のソリューションが検討されてきたが、この研究は非常に有望な治療オプションを指摘している。シカゴ大学のプリツカー分子工学大学院(PME)の研究チームは、最先端のコンピューターシミュレーションを使用して、この世界的なパンデミックの解決策を迅速に追跡できる既存の薬物を特定した。 彼らの発見は、2020年8月14日にScience…

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