Impact of COVID-19 on Heart Failure Patients in South Korea


Posted: 2021-09-21 19:00:00
Int Heart J . 2021 Sep 17. doi: 10.1536/ihj.21-198. Online ahead of print. Affiliations Expand Affiliations 1 Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine. 2 Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology. Item in Clipboard Minkook Son et al. Int Heart J. 2021. Show details Display options Display options Format Int Heart J . 2021 Sep 17. doi: 10.1536/ihj.21-198. Online ahead of print. Affiliations 1 Division of Cardiology, Department of Internal Medicine, Dong-A University College of Medicine. 2 Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology. Item in Clipboard CiteDisplay options Display options Format Abstract Cardiovascular diseases can affect the clinical course of coronavirus disease 2019 (COVID-19); however, evaluation of COVID-19 contribution to prognosis for each individual disease, such as heart failure, is lacking in South Korea. Therefore, this study aimed to investigate COVID-19 patients with heart failure by matching them with patients with heart failure only and those with COVID-19 only. We performed a nationwide population-based retrospective study using data from the National Health Insurance System. Based on patients with heart failure and COVID-19, up to 1:3 propensity score matching procedures were performed for patients with heart failure only and those with COVID-19 only. The outcome was the composite of complications. After matching, a multivariable-adjusted conditional logistic regression analysis was performed. The number of patients was 317 for heart failure and COVID-19, 951 for heart failure only, and 884 for COVID-19 only. The adjusted odds ratio (OR) and 95% confidence interval (CI) for the composite of complications of patients with heart failure and COVID-19 compared with those with heart failure only was 3.511 (2.501-4.928), and compared with those with COVID-19 only, they were 1.626 (1.112-2.376). In patients with heart failure and COVID-19, age per 10 years increase and diabetes were significant variables with the adjusted OR (95% CI) [2.206 (1.704-2.856) for age and 2.345 (1.244-4.420) for diabetes] for complications. This study demonstrated that patients with both heart failure and COVID-19 in South Korea are associated with a poor prognosis. Patients with heart failure require more surveillance and precautions for COVID-19, as recommended by the Center for Disease Control and Prevention. Keywords: Case-control study; Prognosis; Propensity score matching.

参考サイト PubMed: covid-19



バイオクイックニュース日本語版:COVID-19特集

バイオクイックニュース日本語版
3月 27, 2020 バイオアソシエイツ

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