Frequency of respiratory pathogens other than SARS-CoV-2 detected during COVID-19 testing


Posted: 2021-11-20 20:00:00
Diagn Microbiol Infect Dis . 2021 Oct 22;102(2):115576. doi: 10.1016/j.diagmicrobio.2021.115576. Online ahead of print. Affiliations Expand Affiliations 1 Laboratory of Cell and Molecular Tumor Biology and Bioactive Compounds, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil; Laboratory of Human and Medical Genetics, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil. 2 BioISI - Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon, Lisbon, Portugal. 3 Pulmonology and Allergy Pediatric Center, Campinas, São Paulo, Brazil. 4 Center for Investigation in Pediatrics, School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil. 5 Laboratory of Cell and Molecular Tumor Biology and Bioactive Compounds, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil; Laboratory of Human and Medical Genetics, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil. Electronic address: fernando.marson@usf.edu.br. Item in Clipboard Matheus Negri Boschiero et al. Diagn Microbiol Infect Dis. 2021. Show details Display options Display options Format Diagn Microbiol Infect Dis . 2021 Oct 22;102(2):115576. doi: 10.1016/j.diagmicrobio.2021.115576. Online ahead of print. Affiliations 1 Laboratory of Cell and Molecular Tumor Biology and Bioactive Compounds, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil; Laboratory of Human and Medical Genetics, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil. 2 BioISI - Biosystems & Integrative Sciences Institute, Faculty of Sciences, University of Lisbon, Lisbon, Portugal. 3 Pulmonology and Allergy Pediatric Center, Campinas, São Paulo, Brazil. 4 Center for Investigation in Pediatrics, School of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil. 5 Laboratory of Cell and Molecular Tumor Biology and Bioactive Compounds, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil; Laboratory of Human and Medical Genetics, Universidade São Francisco, Bragança Paulista, São Paulo, Brazil. Electronic address: fernando.marson@usf.edu.br. Item in Clipboard CiteDisplay options Display options Format Abstract The frequencies of 19 respiratory pathogens other than SARS-CoV-2 were assessed in 6,"?>235 Brazilian individuals tested for COVID-19. Overall, only 83 individuals who tested positive for SARS-CoV-2 had codetection of other pathogens. Individuals infected with Rhinovirus/Enterovirus, Human Coronavirus (HCoV)-HKU1, HCoV-NL63, HPIV-4, Influenza A (-H1N1 and other subtypes), Influenza B, Human Respiratory Syncytial Virus and Human Metapneumovirus were less likely to test positive for SARS-CoV-2. Infection with Streptococcys pyogenes, Chlamydophila pneumoniae, Mycoplasma pneumoniae, and Bordetella pertussis were more frequent in individuals who tested negative for SARS-CoV-2, but without significancy. We found 150 individuals infected with ≥2 pathogens other than SARS-CoV-2, only 3 out of whom tested positive for COVID-19. The codetection frequency was low in individuals diagnosed with COVID-19. Other viral infections may provide a cross-reactive, protective immune response against SARS-CoV-2. Screening for bacterial respiratory infections upon COVID-19 testing is important to drive suitable therapeutic approaches and avoid unnecessary antibiotic prescription. Keywords: COVID-19; Codetection; Pandemic; SARS-CoV-2. Copyright © 2021 Elsevier Inc. All rights reserved. Conflict of interest statement Declaration of competing interest The authors report no conflicts of interest relevant to this article. [x] Cite Copy Format: Send To [x]

参考サイト PubMed: covid-19


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バイオクイックニュース日本語版:COVID-19特集

バイオクイックニュース日本語版
8月 05, 2020 バイオアソシエイツ

コウモリのウイルス耐性と長寿命が、新型コロナウイルスへのヒントを提供するとの展望が発表された

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