A case with SARS-CoV-2 reinfection from India


Posted: 2021-11-18 20:00:00
Case Reports Indian J Med Microbiol . 2021 Nov 15;S0255-0857(21)04647-8. doi: 10.1016/j.ijmmb.2021.09.010. Online ahead of print. Affiliations Expand Affiliations 1 Indian Council of Medical Research-National Institute of Virology, Bangalore Unit, Karnataka, 560029, India. Electronic address: ashokmniv@gmail.com. 2 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: dr.rima.sahay@gmail.com. 3 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: gndeshpande@gmail.com. 4 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: patildeepak8@gmail.com. 5 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: anitaaich2008@gmail.com. 6 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: gajanansapkalniv@gmail.com. 7 Employees' State Insurance Corporation Medical College and Hospital, Gulbarga, Karnataka, 585106, India. Electronic address: drravish@rocketmail.com. 8 Employees' State Insurance Corporation Medical College and Hospital, Gulbarga, Karnataka, 585106, India. Electronic address: marappa003@gmail.com. 9 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: hellopragya22@gmail.com. 10 Employees' State Insurance Corporation Medical College and Hospital, Gulbarga, Karnataka, 585106, India. Electronic address: shettarv@gmail.com. Item in Clipboard Case Reports Ashok Munivenkatappa et al. Indian J Med Microbiol. 2021. Show details Display options Display options Format Indian J Med Microbiol . 2021 Nov 15;S0255-0857(21)04647-8. doi: 10.1016/j.ijmmb.2021.09.010. Online ahead of print. Affiliations 1 Indian Council of Medical Research-National Institute of Virology, Bangalore Unit, Karnataka, 560029, India. Electronic address: ashokmniv@gmail.com. 2 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: dr.rima.sahay@gmail.com. 3 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: gndeshpande@gmail.com. 4 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: patildeepak8@gmail.com. 5 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: anitaaich2008@gmail.com. 6 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: gajanansapkalniv@gmail.com. 7 Employees' State Insurance Corporation Medical College and Hospital, Gulbarga, Karnataka, 585106, India. Electronic address: drravish@rocketmail.com. 8 Employees' State Insurance Corporation Medical College and Hospital, Gulbarga, Karnataka, 585106, India. Electronic address: marappa003@gmail.com. 9 Indian Council of Medical Research-National Institute of Virology, Pune, Maharashtra, 411021, India. Electronic address: hellopragya22@gmail.com. 10 Employees' State Insurance Corporation Medical College and Hospital, Gulbarga, Karnataka, 585106, India. Electronic address: shettarv@gmail.com. Item in Clipboard CiteDisplay options Display options Format Abstract A healthcare worker presented with fever, cough, headache and tested positive by SARS-CoV-2 real time reverse transcriptase polymerase chain reaction (qRT-PCR). He got admitted to hospital and recovered after 14 days. After 2 months, as a screening protocol considering the high risk setup he got tested and again found to be positive for SARS-CoV-2 by qRT-PCR. Our patient had detectable levels of Anti-SARS-CoV-2 IgG antibodies during the reinfection but found negative for Neutralizing antibodies (NAb). Our findings suggest that the person after the initial infection might not develop the desired protective immunity to prevent the reinfection as demonstrated by absence of NAb. Keywords: COVID-19; IgG antibodies; India; Reinfection; SARS-CoV-2. Copyright © 2021 Indian Association of Medical Microbiologists. Published by Elsevier B.V. All rights reserved. Conflict of interest statement Declaration of competing interest None. Publication types Case Reports [x] Cite Copy Format: Send To [x]

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