... shown that a method they developed to improve the usefulness and precision of the most common form of the gene-editing tools CRISPR-Cas9 RNA-guided nucleases can be applied to Cas9 enzymes from other bacterial sources. In an article published online ...
... on August 27, 2015 in Angewandte Chemie. The article is titled “Self-Assembled DNA Nanoclews for the Efficient Delivery of CRISPR-Cas9 for Genome Editing." The CRISPR/Cas system, which is found in bacteria and archaea, protects bacteria from invade ...
... titled “Functional Correction of Large Factor VIII Gene Chromosomal Inversions in Hemophilia A Patient-Derived iPSCs Using CRISPR-Cas9.” It published online on July 23, 2015 in Cell Stem Cell. Sufferers of hemophilia live in a perpetual state of ...
... genetics research. The research was published online on July 13, 2015 in Nature Methods. The article is titled “Unraveling CRISPR-Cas9 Genome Engineering Parameters via a Library-on-Library Approach.” The study describes a way to simplify a labor ...
... e the CRISPR toolbox accessible for in vivo experimental and therapeutic applications. Originally discovered in bacteria, the CRISPR-Cas9 system enables the cutting of DNA as a defense mechanism against viral infection. Although numerous microbial spe ...